The Peripheral Artery Questionnaire (PAQ)

The Peripheral Artery Questionnaire is the most sensitive, specific, and responsive health-related quality of life measure for peripheral artery disease.


The Peripheral Artery Questionnaire (PAQ) is a 20-item questionnaire developed to meet this need by quantifying patients’ physical limitations, symptoms, social function, treatment satisfaction, and quality of life.

Psychometric and clinical properties of the PAQ were evaluated in a prospective cohort study of 44 patients undergoing elective percutaneous peripheral revascularization. To establish reproducibility, 2 assessments were performed 2 weeks apart and before revascularization. The change in scores before and 6 weeks after revascularization were used to determine the instruments’ responsiveness and were compared with the Short Form-36 and the Walking Impairment Questionnaire. A series of cross-sectional analyses were performed to establish the construct validity of the PAQ.


The 7 domains of the PAQ were internally reliable, with Cronbach α = 0.80 to 0.94. The test-retest reliability
analyses revealed insignificant mean changes of 0.6 to 2.3 points (P = not significant for all). Conversely, the change after revascularization ranged from 13.7 to 41.9 points (P ≤ .001 for all), reflecting substantial sensitivity of the PAQ to clinical improvement. The PAQ Summary Scale was the most sensitive of all scales tested. Construct validity was established by demonstrating correlations with other measures of patient health status.

Reliability and Responsiveness

The internal reliability of the PAQ domains ranged from a low of 0.80 for the PAQ Symptom Scale to a high of 0.94 for the PAQ Summary Scale. The test-retest reliability of the PAQ domains was also high. The mean change in scores over 2 weeks of observation ranged from 0.9 to 2.2 points on a 100-point scale.

Created: April 29, 2004 03:45
Last updated: December 02, 2018 20:07


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